Planners are "intensively" looking at creating a segregated cycle lane along the entire length of Byres Road.
Such a structure would likely see the removal of most if not all of the road's parking bays.
Green councillor Christy Mearns pushed cross-party backing for the measure at committee this week.
But sustainable transport convenor Cllr Anna Richardson said the council had always had the lanes firmly in mind.
The move came as findings of a public consultation on a £9 million improvement scheme for Byres Road were revealed.
Cllr Richardson told Glasgow West End Today: "We have always been looking at segregated cycle lanes as one of the many options that were always on the table.
"Throughout this process we've been looking at ways to balance all the different needs of all the different people who use Byres Road.
"Certainly now as a result of the consultation responses, we've got a very clear message that segregation would be welcomed.
"So that is something that we are looking at more intensively."
Motorists and taxi drivers have got most to lose if parking bays and a taxi rank make way for a segregated lanes.
Some businesses will also say that trade will be affected.
But the SNP-led council believes better walking and cycling provision would be good for the environment and good for business.
The Scottish government has said it wants to see more journeys made by means of so-called active travel.
The improvement scheme, being paid for by City Deal cash, was launched last January.
But the process is likely to be a year behind schedule because of the challenges faced by planners.
Initial proposals for Byres Road worked up following consultations in the spring were presented to the council in the summer.
They included wider pavements, less street furniture and friendlier crossings for elderly people and vulnerable users.
But there was no segregated cycle lane, just a non-protected lane for those on two wheels.
Cllr Richardson said: "Since the consultation responses came back and were analysed over the past six to eight weeks we have been looking at various options to introduce segregation - so it is very much still on the table.
"With any street you have got to make compromises and you've got to find ways of meeting as many needs as possible.
"What the consultation response has given us is a public mandate to increase the priority of walking and cycling on that street."
She said planners would look at the parking needs of the wider area around Byres Road before formalising a scheme.
She said: "We need to think about what parking provision is available for those who need their cars to reach the area.
"At the same time, we've made it very clear as a city that we're prioritising sustainable transport - that's walking, cycling and public transport.
"We want to make it as easy as possible for people to use those modes to and through Byres Road."
Green councillor Christy Mearns said: "I'm delighted to have won a commitment for fully segregated cycle lanes and air quality monitoring along the length of Byres Road.
"It is essential that cycling is made a safer and more attractive option if we are to reduce traffic congestion on our high streets and tackle toxic levels of air pollution."
Cycling campaigners had previously protested at the lack of segregated provision within the original plans.
Iona Shepherd, convenor of the cycling pressure group GoBike, said: "We are relieved that plans for Byres Road are being looked at again in order to give active travel it’s rightful space in our people friendly places.
"Byres Road could be a key route within a slowly growing safe network for cycling within Glasgow, but without fully segregated cycle lanes and a reduction in through traffic, the high rates of accidents and pollution in the area will remain.
"For Byres Road to be a truly liveable street where businesses will thrive, people of all ages and abilities must have the option to safely travel there on foot or by bike."
https://youtu.be/0EoG2Da2lzU
Watch: Cllr Anna Richardson talks about plans for a segregated cycle lane
Comments on social media suggest not everyone thinks prioritising people on bicycles over cars is a good idea.
One said the move would be "catastrophic" for Byres Road.
